Determination factors of affecting the risks of non-recovery in cutaneous leishmaniasis patients using binary logistic regression (Published Online: 2018 July 26)
Mustafa Aksoy1, Abdullah Yesilova2, Yavuz Yesilova3, Isa An4
1Harran University, Faculty of Medicine Department of Dermatology, Sanliurfa, Turkey
2Yüzüncü Yıl University, Faculty of Agriculture Biometry and Genetics Unit Van, Turkey
3Department of Dermatology, Special Locator Physician Hospital, Van, Turkey
4Akcakale State Hospital Clinic of Dermatology, Sanliurfa, Turkey
Aim: This article aimed to make an assessment by applying the binary logistic regression from the studies reported for cutaneous leishmaniasis patients in the province of Şanlıurfa.
Material and Methods: The age and sex, the type, localization, diameter and number of lesions as well as treatments of 8000 cutaneous leishmaniasis patients were retrospectively recorded in this study. The risk of non-recovery for intralesional (IL) and intramuscular (IM) groups according to independent variables were assessed using a binary logistic regression.
Results: While there was no difference in non-recuperation risk of IL group between genders, males were 39.4% more likely to recuperate than females among the patients belonging to IM groups. All age groups, non-recuperation risk of children were decreased according to the reference level in IL group. As for the IM treatment, non-recovery risk was considered statistically insignificant. During the disease of the patients receiving both IL and IM treatments, non-recuperation risk of the patients of all-week groups was high according to the reference level. When the head and neck region was taken as reference level, the regions with the highest non-recuperation risk of the lesion for IL and IM was identified as generalized and trunk, respectively.
Conclusions: The treatment success rate is inversely proportional with the lesion duration in both IL and IM treatments. There was decreasing in the success rates of both treatments as a result of an increased in lesion size. Increased lesion diameter results in decreased success rates with both treatments.