Age related risk factors associated with severity of atopic dermatitis in children
Mehmet Halil Celiksoy1, Erdem Topal2, Osman Demir1
1Gaziosmanpasa Taksim Training and Research Hospital, Department of Pediatrics, Istanbul, Turkey
2Inonu University, Faculty of Medicine, Department of Pediatric Health and Diseases, Malatya, Turkey
Aim: Atopic dermatitis is a chronic, relapsing, and pruritic dermatitis, which generally develops in early childhood, and has a characteristic age-dependent distribution. To review age related risk factors associated with severity of atopic dermatitis in children.
Material and Methods: The medical records of 206 pediatric patients with the diagnosis of atopic dermatitis between August 2015 and August 2017 were reviewed retrospectively.
Results: The study included two hundred six patients who were diagnosed with atopic dermatitis (118 males, 88 females, median age: 20 months). The disease was found to have a more severe course in patients who were breastfed for less than six months, who were exposed to cigarette smoke, who had a food allergen and a history of atopy in the family (p<0.047, 0.046, 0.032, 0.012, respectively) in the 0-2 age group. The disease was found to have a more severe course in patients who had aeroallergen sensitivity, high serum total IgE level, who had eosinophilia, and low socioeconomic level (p<0.016, 0.023, 0.038, 0.032, respectively) in the patient older than 2 years old.
Conclusion: While parental atopy and diet determine the severity of the disease in the early period of life, environmental factors have a more obvious role in later periods.