Comparison of the effects of adding fentanyl or remifentanil to propofol in colonoscopy sedoanalgesia
on visual analog scale and recovery: A prospective double-blind study (Published Online: 2019 February 15)
Mukadder Sanli, Muharrem Ucar
Inonu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Malatya, Turkey
Aim: In this study; our aim is to compare the effects of fentanyl or remifentanil combinations added to propofol in sedoanalgesia of colonoscopy on the visual analog scoring (VAS) and recovery of the patient.
Material and Methods: Seventy patients aged between 18 and 65 who had colonoscopy were included in the study. 1 mg/kg propofol and 1 mcg/kg fentanyl, and 1 mg/kg propofol and 1 mcg/kg remifentanil were given as bolus to Group PF and Group PR, respectively. The respiratory and hemodynamic data during the procedure, and additionally pain and recovery criteria evaluated by VAS and Observer’s Assessment of Alertness/Sedation Scale (OAA / S) scores were compared at the end of the procedure.
Results: There was a significant difference between the groups at 5th, 15th and 30th minutes in terms of VAS scores (p <0.001). There was a significant difference between the groups in terms of OAA / S scores at 5th and 15th min (p <0.001). The OAA / S scores were similar in both groups at 30th min and there was no difference (p = 1.00).
Conclusion: Combination of propofol with fentanyl or remifentanil in sedoanalgesia of colonoscopy provides a safe and comfortable examination. Early recovery in both groups is advantageous as they provide early discharge.