Neutrophil / Iymphocyte ratio, platelet / Iymphocyte ratio, mean platelet volume and C-reactive protein values in psoriatic arthritis patients
Isa An1, Derya Ucmak2, Murat Ozturk3, Mustafa Aksoy4, Ismail Yildiz5, Egemen Ucan2
1Sanliurfa Training and Research Hospital, Department of Dermatology, Sanliurfa, Turkey
2Dicle University Faculty of Medicine, Department of Dermatology, Diyarbakir, Turkey
3Van Training and Reserch Hospital, Department of Dermatology, Van, Turkey
4Harran University Faculty of Medicine, Department of Dermatology, Sanliurfa, Turkey
5Dicle University Medical Faculty, Department of Biostatistics and Medical Informatics, Diyarbakir, Turkey
Aim: Studies have shown that neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio(PLR), mean platelet volume(MPV) and C-reactive protein(CRP) are higher in psoriatic arthritis patients than in the control group. In this study, NLR, PLR and MPV values of patients with psoriatic arthritis were calculated and if these parameters were related to CRP levels.
Material and Methods: 74 psoriatic arthritis patients and 77 healthy controls without any systemic, infectious and autoimmune diseases were included in the study. Patients were divided into two groups according to their CRP values: normal (0-0.5 mg / dl) and high (> 0.5 mg / dl)
Results: NLR, MPV and CRP values in the patient group were significantly higher than the control group. PLR value in the patient group was higher than the control group but the difference between them was not statistically significant. There was a statistically significant relationship between CRP and NLR and MPV values in psoriatic arthritis patients.
Conclusion: Since NLR and MPV were significantly higher in psoriatic arthritis patients than in the control group and there was a statistically significant relationship with CRP elevation, it was thought that they were appropriate parameters to show inflammation in patients with psoriatic arthritis.