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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia (p.471-5)

The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia (p.471-5)

Ahmet Gurdal, Kudret Keskin, Serhat Sigirci, Sukru Cetin, Kadriye Orta Kilickesmez
University of Health Sciences, Sisli Hamidiye Etfal Education and Research Hospital, Department of Cardiology, Istanbul, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.


Aim: The pathophysiology of coronary artery ectasia (CAE) has not been clear. Dyslipidemia is a serious cause for increasing the risk of coronary artery disease. The relationship between isolated CAE and dyslipidemia is unknown. We evaluated the triglyceride to high-density lipoprotein cholesterol ratio (Tg to HDLc) and dyslipidemia in patients with isolated CAE.
Material and Methods: We included 60 patients and 70 controls with normal coronary arteries with similar baseline risk factors. Total cholesterol (Tc), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (Tg) levels were measured and Tg to HDLc ratio was calculated. Factors predicting CAE were analyzed.
Results: When compared with the controls serum Tg level and Tg to HDLc ratio were significantly higher, HDLc level was significantly lower in the patients (p=0.001; p=0.004; p=0.001, an respectively). The multivariate logistic regression analysis revealed that Tg to HDLc ratio (OR:1.476, 95% CI 0.1199-1.817, p=0.001) was independent factor predicting isolated CAE. In the ROC curve analysis, Tg to HDLC ratio was found to be statistically significant with a cut-off point value of 4.2 was determined to predict isolated CAE [AUC=0.829, (95% CI, 0.752-0.906), p=0.001].
Conclusion: Tg to HDLc ratio, HDLc and triglycerides were found to be independent factors predicting isolated CAE. These lipid parameters and Tg to HDLc ratio may be a valuable, easily accessible, non-invasive way of predicting the presence of isolated CAE.

Keywords: Coronary artery disease; coronary artery ectasia; dyslipidemia; triglyceride



doi: 10.5455/annalsmedres.2019.12.864



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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