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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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The frequency of thyroid autoimmunity in behcet’s disease in mid-anatolian region of Turkey (p.977-9)

The frequency of thyroid autoimmunity in behcet’s disease in mid-anatolian region of Turkey (p.977-9)

Gulcan Saylam Kurtipek1, Fatma Tuncez Akyurek1, Huseyin Kurku
1Selcuk University, Faculty of Medicine, Department of Dermatology, Konya, Turkey
2Konya Training and Research Hospital, Clinic of Biochemistry, Konya, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.


Aim: Behcet’s disease is considered a vasculitis triggered by immunological mechanisms; however its pathogenesis has not been elucidated. The thyroid autoimmune disease frequently coexists with various autoimmune conditions. Studies on the effect of Behcet’s disease on this gland are limited. The present study aimed to examine the presence of thyroid autoimmunity in Behset’s Disease, which has been recently regarded as an autoimmune disease.
Material and Methods: The study included 45 patients diagnosed with Behcet’s disease according to the criteria of the International Study Group, and 42 healthy individuals. The levels of FT3, FT4, TSH, thyroglobulin autoantibody (anti-TG) and anti-thyroid peroxidase antibody (anti-TPO), and results of thyroid ultrasonography were examined in all patients and healthy individuals.
Results: No significant difference was found in the levels of FT3, TSH and thyroid autoantibodies (anti-TG, anti-TPO) of thyroid function tests between the two groups. FT4 levels were significantly higher in patients with Behcet’s disease compared to the control group (p=0.029).
Conclusion: The present study showed that there was no concomitant autoimmune thyroid disease in patients with Behcet’s disease. However, we believe that the vasculitis process might have an impact on parenchyma of the thyroid since FT4 levels were significantly higher in patients, and thus parenchyma of the thyroid should be examined thoroughly in patients with Behcet’s disease.
Keywords: Autoimmunity; behcet’s disease; thyroid



doi: 10.5455/annalsmedres.2019.10.651



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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