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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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Kounis syndrome in a patient with secondary mast cell activation syndrome after a bee sting (p.1286-9)

Kounis syndrome in a patient with secondary mast cell activation syndrome after a bee sting (p.1286-9)

Gokhan Aytekin1, Fatih Colkesen1, Eray Yildiz1, Sevket Arslan1, Pembe Oltulu2 
1Necmettin Erbakan University, Meram Faculty of Medicine, Department of Internal Medicine, Division of Clinical Immunology and Allergy, Konya, Turkey
2Necmettin Erbakan University, Meram Faculty of Medicine, Department of Pthology, Konya, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

A 64-year-old male patient was admitted to our clinic with complaints of hot flashes all over the body, fainting and loss of consciousness after a bee sting. The patient who had no history of coronary artery disease was fitted with a stent in the LAD coronary artery with a percutaneous coronary angioplasty by complaints of chest pain and shortness of breath after the bee sting. I3 Vespula spp (yellow jacket) in serum was positive at 0.39 kUA / L-class 1. Tryptase levels were elevated at 19.5/g/L during the asymptomatic period. After the tryptase levels remained elevated at 49.2/g/L during the asymptomatic period after 4 weeks. The bone marrow biopsy revealed a mast cell ratio of 2%. Based on the patient’s history, physical examination and laboratory findings, the patient was considered to have Kounis syndrome, mast cell activation syndrome and a venom allergy.

Keywords: Hymenoptera venom allergy; kounis syndrome; mast cell activation syndrome; omalizumab 

 

 

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doi: 10.5455/annalsmedres.2019.10.671  

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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