1Necmettin Erbakan University, Meram Faculty of Medicine, Department of Internal Medicine, Division of Clinical Immunology and Allergy, Konya, Turkey
2Necmettin Erbakan University, Meram Faculty of Medicine, Department of Pthology, Konya, Turkey
A 64-year-old male patient was admitted to our clinic with complaints of hot flashes all over the body, fainting and loss of consciousness after a bee sting. The patient who had no history of coronary artery disease was fitted with a stent in the LAD coronary artery with a percutaneous coronary angioplasty by complaints of chest pain and shortness of breath after the bee sting. I3 Vespula spp (yellow jacket) in serum was positive at 0.39 kUA / L-class 1. Tryptase levels were elevated at 19.5/g/L during the asymptomatic period. After the tryptase levels remained elevated at 49.2/g/L during the asymptomatic period after 4 weeks. The bone marrow biopsy revealed a mast cell ratio of 2%. Based on the patient’s history, physical examination and laboratory findings, the patient was considered to have Kounis syndrome, mast cell activation syndrome and a venom allergy.
Keywords: Hymenoptera venom allergy; kounis syndrome; mast cell activation syndrome; omalizumab