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Investigation of the characteristics differentiating complicated and non-complicated appendicitis: A prospective analysis (p.1333-7)

Investigation of the characteristics differentiating complicated and non-complicated appendicitis: A prospective analysis (p.1333-7)

Kasım Turgut1, Sabri Ozdas2, Mehmet Sirik3, Irfan Aydin1
1Adiyaman University Education Research Hospital, Department of Emergency Service, Adiyaman, Turkey
2Adiyaman University Education Research Hospital, Department of General Surgery, Adiyaman, Turkey
3Adiyaman University Education Research Hospital, Department of Radiology, Adiyaman, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.


Aim: To investigate preoperative laboratory and clinical results and imaging methods in patients with complicated and non-complicated appendicitis.
Materials and Methods: A total of 141 patients aged over 16 years, who underwent surgery with the diagnosis of acute appendicitis, were included in the study. In patients diagnosed with acute appendicitis based on physical examination and laboratory findings, abdominal contrast-enhanced tomography was performed for confirmation and differential diagnosis. Age, gender, body temperature, complaint, duration of complaint, number of white blood cells, the largest diameter of appendicitis measured on computed tomography (CT), Alvarado score, and recurrent admission to any health institution with the same complaint were recorded. Intraoperative findings and pathology reports were evaluated to determine whether the appendicitis was complicated, and the cases were divided into two groups as complicated and non-complicated.
Results: Totally 141 patients were included in the study, 39 cases were classified as complicated and 102 cases as non-complicated appendicitis. There were more people with high fever in the complicated group (p=0.023). The median of largest appendicitis diameter measured on the CT was 8.5 (5.5-15) mm, and a significant difference was determined between the two groups in terms of diameter (p0.001). The median time from the onset of the complaints to the emergency department presentation was 12 hours, and this duration was significantly longer in the complicated group (p0.001). Analysis of receiver operating characteristic curves yielded the cutoff values of 8.35 mm for diameter (area under the curve [AUC]: 0.860; sensitivity: 87.2%; specificity: 63.7%), and 10.5 hours for time interval (AUC: 0.868; sensitivity: 97.4%; specificity: 64.7%) were found to be the best predictive values for the complicated acute appendicitis determination.
Conclusion: In patients diagnosed with acute appendicitis, necessary interventions should be immediately undertaken, especially in the presence of fever, increased appendicitis diameter, and delayed presentation to hospital.

Keywords: Antioxidant; disulphide; hearing loss; thiol; tinnitus


doi: 10.5455/annalsmedres.2020.01.09       



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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