• E-ISSN 2636-7688

Formerly Journal of Turgut Ozal Medical Center

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Avascular necrosis of the femoral head in sickle cell disease  (p. 79-80)

Avascular necrosis of the femoral head in sickle cell disease (p. 79-80)

Neslihan Karakurt1, Mehmet Ali Deveci2

1Hitit University Çorum Training and Research Hospital, Pediatric Hematology, Oncology, Çorum, Turkey

2Çukurova University, Faculty of Medicine, Orthopaedics and Traumatology Department, Adana, Turkey



Sickle cell disease (SCD) is a life threatening hemoglobinopathy effecting various systems. SCD is an important health issue in Turkey, especially in the southern areas. The patients suffer from complications resulting from vaso-occlusion and hemolysis. Twenty- two percent of children and 49% of adults with Hb SS are reported to have avascular necrosis (AVN). The SCD panel 2014 recommends to evaluate all children with SCD and hip pain for AVN by history, physical examination, radiography and magnetic resonance imaging. Long term daily oral treatment with hydroxyurea has been shown to reduce complications in SCD. Hydroxyurea does not only increase the level of fetal hemoblobin but also it causes a reduction in the number of circulating leukocytes, increases red blood cell size. Here in two SCD patients who developed AVN in femoral head are reported and it is aimed to raise awareness to this morbidity and the importance of regular use and dosage escalation of hydroxyurea therapy.

Keywords: Sickle Cell Disease; Avascular Necrosis; Pediatrics.


doi: 10.5455/jtomc.2016.08.091



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.



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