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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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Information on local anesthetics and toxicity for doctors in surgical department of Karadeniz Technical University Medical Faculty Hospital (p.1811-5)

Information on local anesthetics and toxicity for doctors in surgical department of Karadeniz Technical University Medical Faculty Hospital (p.1811-5)

Sibel Buran1, Ali Akdogan2, Ahmet Besir2, Davut Dohman2
1Clinic of Anesthesiology ,Arakli State Hospital, Trabzon, Turkey
2Department of Anesthesiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.


Aim: Local anesthetics are commonly used in surgical interventions and anesthesia applications. The aim of this study was to increase the sensitivity of local anesthetic toxicity to the presence of symptoms, precautions to be taken and the use of 20% lipid infusion for treatment.
Material and Methods: The questionnaire was applied on 160 of 205 physicians who were prescribed local anesthetics.
Results: Of the 160 participants included in the study, 108 (67.5%) were research assistants, 47 (29.4%) were faculty members and the remaining 5 (3.1%) were expert medical practitioners. 63 of the participants (39.4%) had been working in the medical profession for more than 5 years. While 42.5% of the participants administered local anesthetics every day, 33.1% had not received any training in the area. On the basis of their training status, it was the anesthetists among specialist doctors who were the most trained in anesthetics with a statistically high rate of 86.3%.
Thirty-three of the surveyed physicians (20.6%) who responded stated that they had experienced a case of local anesthetic toxicity previously. The most frequent answer to the question in early findings concerning local anesthetic toxicity was anaphylaxis (74.4%). 38.1% of the participants had not heard the use of 20% lipid solution in local anesthetic toxicity. Although there was 20% lipid solution in the university hospital where the research was conducted, 31.9% of the participants knew this.
Conclusion: Although local anesthetic toxicity is rare, it frequently occurs in clinical practice. Therefore, physicians should have general knowledge regarding local anesthetic drugs, maximum doses, side effects, toxicity symptoms and the required treatment in the case of toxicity. We also think local anesthetic toxicity should be included in annual training programs and practical applications by other clinical branches that apply local anesthetic drugs as we currently do at our Clinic and physicians should be given appropriate guidance.

Keywords: Intralipid; local anesthetic; toxicity; questionnaire



doi: 10.5455/annalsmedres.2019.12.905



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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