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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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A case of gliosarcoma in a child with neurofibromatosis type 1 (p.2214-7)

A case of gliosarcoma in a child with neurofibromatosis type 1 (p.2214-7)

Gulec Mert Dogan1, Ahmet Sigirci1, Aslinur Cengiz1, Mehmet Fatih Erbay2, Hasan Gokce3
1Department of Pediatric Radiology, Faculty of Medicine, Inonu University, Malatya, Turkey
2Department of Radiology, Faculty of Medicine, Inonu University, Malatya, Turkey
3Department of Patology, Faculty of Medicine, Inonu University, Malatya, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Gliosarcoma (GS) is a rarely seen form of glioblastoma. These tumors are mostly seen in males older than 60 years of age. It is extremely rare in pediatric central nervous system (CNS) tumors. In this case report, we present a 3-year-old boy with a giant gliosarcoma. Magnetic resonance (MR) imaging and histopathologic findings are discussed. A 3 year-old boy with a clinically diagnosed NF-1 was admitted to the emergency department with a complaint of intractable vomiting. Magnetic resonance imaging (MRI) of the brain was suggestive of a large lobulated mass lesion in the left parietal lobe extending to the vertex and slightly compressing the left lateral ventricle. The final histopathologic diagnosis of the tumor was considered as gliosarcoma. To our knowledge, this case constitutes the first youngest case with neurofibromatosis type 1 reported in the literature in all pediatric cases of GS.

Keywords: Gliosarcoma; magnetic resonance imaging; neurofibromatosis 1 

 

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doi: 10.5455/annalsmedres.2020.02.128

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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