1Muş Devlet Hastanesi, Acil Servis, Muş, Türkiye
2İnönü Üniversitesi Tıp Fakültesi, Acil Tıp Anabilim Dalı, Malatya, Türkiye
3İnönü Üniversitesi Tıp Fakültesi, Biyoistatistik ve Tıp Bilişimi Anabilim Dalı, Malatya, Türkiye
4İnönü Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Malatya, Türkiye
5İzmit Seka Devlet Hastanesi, Acil Servis, Kocaeli, Türkiye
Objective: Stroke is the third leading cause of death and one of the most important causes of long-term disability. In our study, the aim is to identify the risk factors that cause ischemic stroke to determine the risk of stroke in the presence of multiple risk factors.
Materials and Methods: In this study, a total of 260 patients were examined; 120 of these patients were, as the patient group, diagnosed with ischemic stroke in the emergency department, and 140 of them constituted the control group. Data concerning physical examination results and medical history including previous history of cerebrovascular disease (CVD), coronary artery disease (CAD), diabetes mellitus (DM), hypertension (HT), atrial fibrillation (AF), and smoking, were obtained. High density lipoprotein (HDL), international normalized ratio (INR), C-reactive protein (CRP), protein C, protein S, antithrombin III (AT3) levels were measured. Electrocardiography (ECG), brain tomography, and carotid Doppler ultrasonography (USG) were performed.
Results: In our study, CAD (p0.001), DM (p0.001), CVD history (p0.001), smoking (p=0.004), presence of carotid plaque or plaques and/or stenosis (≥50%) (p0001), and low HDL levels (p=0.014) were found to be statistically significant. On the univariate logistic regression analysis of risk factors, carotid plaque and stenosis presence ≥50% (OddsRatio/Ratio(OR)=32.08) were found to have the highest risk for ischemic stroke. Among the dual risk factors, DM association with smoking was OR=18 and generated much more risk than they cause alone.
Conclusion: These results shows the importance of early detection of ischemic stroke risk factors, especially when the risk factors are coupled, and of planning early stage measures and preventive treatment.
Keywords: Multiple Risk Assessment; İschemic Stroke; Risk Factors.