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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

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The Risk Factors and Their Effects in Ischemic Stroke (p. 225-30)

The Risk Factors and Their Effects in Ischemic Stroke (p. 225-30)

Esra Karaman1, Muhammet Gökhan Turtay2, Cemil Çolak3, Hakan Oğuztürk2, Şükrü Gürbüz2, Suat Kamışlı4, Emrah Çelik5
1Muş Devlet Hastanesi, Acil Servis, Muş, Türkiye
2İnönü Üniversitesi Tıp Fakültesi, Acil Tıp Anabilim Dalı, Malatya, Türkiye
3İnönü Üniversitesi Tıp Fakültesi, Biyoistatistik ve Tıp Bilişimi Anabilim Dalı, Malatya, Türkiye
4İnönü Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Malatya, Türkiye
5İzmit Seka Devlet Hastanesi, Acil Servis, Kocaeli, Türkiye

Objective: Stroke is the third leading cause of death and one of the most important causes of long-term disability. In our study, the aim is to identify the risk factors that cause ischemic stroke to determine the risk of stroke in the presence of multiple risk factors.
Materials and Methods: In this study, a total of 260 patients were examined; 120 of these patients were, as the patient group, diagnosed with ischemic stroke in the emergency department, and 140 of them constituted the control group. Data concerning physical examination results and medical history including previous history of cerebrovascular disease (CVD), coronary artery disease (CAD), diabetes mellitus (DM), hypertension (HT), atrial fibrillation (AF), and smoking, were obtained. High density lipoprotein (HDL), international normalized ratio (INR), C-reactive protein (CRP), protein C, protein S, antithrombin III (AT3) levels were measured. Electrocardiography (ECG), brain tomography, and carotid Doppler ultrasonography (USG) were performed.
Results: In our study, CAD (p0.001), DM (p0.001), CVD history (p0.001), smoking (p=0.004), presence of carotid plaque or plaques and/or stenosis (≥50%) (p0001), and low HDL levels (p=0.014) were found to be statistically significant. On the univariate logistic regression analysis of risk factors, carotid plaque and stenosis presence ≥50% (OddsRatio/Ratio(OR)=32.08) were found to have the highest risk for ischemic stroke. Among the dual risk factors, DM association with smoking was OR=18 and generated much more risk than they cause alone.
Conclusion: These results shows the importance of early detection of ischemic stroke risk factors, especially when the risk factors are coupled, and of planning early stage measures and preventive treatment.
Keywords: Multiple Risk Assessment; İschemic Stroke; Risk Factors.


doi: 10.7247/jtomc.2014.2905



Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.



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