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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research

    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research

    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research

    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Cuneyt Kayaalp


Application of ice and vapocoolant spray to reduce tetanus vaccine pain: A prospective, randomized, controlled, clinical study (pp. 995-8)

Application of ice and vapocoolant spray to reduce tetanus vaccine pain: A prospective, randomized, controlled, clinical study (pp. 995-8)

Mehmet Akcimen, Cihan Bedel, Fatih Selvi
Health Science University Antalya Training And Research Hospital, Department of Emergency Medicine, Antalya, Turkey

Aim: Tetanus is one of the vaccine-preventable diseases, that threatens human health in our country and the world, and one of the most common symptoms after vaccination is localized pain. In this study, we aimed to compare the effectiveness of vapocoolant spray with ice application and control group in reducing the pain during vaccination.
Material and Method: This prospective randomized controlled trial included 292 patients who received tetanus vaccination between January 1st, 2017 and  April 1st, 2017   and who agreed to participate in the study.  Patients were assigned to 3 groups. Before vaccination, vapocoolant spray was applied to Group 1 and ice was applied to Group 2, and application was directly performed to Group 3 (control). The pain at the time of vaccination and at injection was noted between 0-100 using Visual Analogue Scale (VAS).
Results: Of the 315 patients included in the study, 292 fulfilled the inclusion criteria. Patients who were applied ice (5.3 ± 7.1) or vapocoolant spray (4.1 ± 5.4) at the time of intervention had statistically significantly lower VAS values than control group (8 ± 10.6) (p = 0.002; p 0.001, respectively). The mean VAS values during injection, in control patients and ice and vapocoolant spray applied patients were found to be as 9.5 ± 8.11; 6.3 ± 7.4; 11.5 ± 10.2, respectively. VAS values at injection were statistically significantly lower in ice-applied patients than in the control group (p = 0.039).
Conclusions: Both ice and vapocoolant spray reduce pain occurred during tetanus vaccination compared to the control group. With easy and fast applicability, ice and vapocoolant spray can be used to reduce the pain during the tetanus vaccine.
Keywords: Vapocoolant spray; ice; tetanus; vaccine.

doi: 10.5455/annalsmedres.2019.02.112


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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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