Effects of bosentan, sildenafil and their combination on T-wave amplitude and QT ınterval in a rat model of pulmonary hypertension

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Published: 2021-05-25
Keywords:
s: Pulmonary Arterial Hypertension, Rat Model, Sildenafil, Bosentan, Electrocardiography, Echocardiography.

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Derya Karpuz
Olgu Hallioglu
Belgin Buyukakilli
Serkan Gurgul
Bahar Tasdelen

Abstract

Aim: Although, bosentan and sildenafil have been used to treat PAH, the effect of these drugs on electrocardiographic (ECG) changes are still unclear. The aim of this study is to evaluate the effects of bosentan, sildenafil, and their combination on T-wave amplitude and QT interval in rats with monocrotaline (MCT)-induced PAH.

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Vol. 24 No. 1 (2017): March

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Original Articles

CC Attribution-NonCommercial-NoDerivatives 4.0

How to Cite

1.
Effects of bosentan, sildenafil and their combination on T-wave amplitude and QT ınterval in a rat model of pulmonary hypertension . Ann Med Res [Internet]. 2021 May 25 [cited 2026 Apr. 17];24(1):0037-43. Available from: http://www.annalsmedres.org/index.php/aomr/article/view/2158

References