Comparing the effect of office hysteroscopy with endometrial injury versus office hysteroscopy in gonadotropin-induced cycles before intrauterine insemination: A randomized controlled trial

Abstract

Aim: Our aim in this study was to evaluate the implantation success in local endometrial injury in patients undergoing intrauterine insemination following induction of ovulation with gonadotropins.

Materials and Methods: In this prospective randomized controlled study, 62 patients undergoing gonadotropin-assisted ovulation induction after intrauterine insemination were included. Thirty patients with hysteroscopy-related injuries were included in Group 1 and 32 control patients who underwent hysteroscopy alone were included in Group 2.

Results: The rates of clinical pregnancy (16.6% [5/30] vs. 18.7% [6/32]; p = 0.8), abortion (3.3% [1/30] vs. 3.1% [1/32]; p = 0.9), and multiple pregnancy (3.3% [1/30] vs. 3.1% [1/32]; p = 0.9) were similar between the two groups.

Conclusion: There were no significant differences in clinical pregnancy, multiple pregnancy, or abortion rates between the groups. The intervention group underwent hysteroscopic injury in the follicular phase before gonadotropin-induced intrauterine insemination, while the control group underwent hysteroscopy only.