Evaluation of posterior segment ocular parameters in pediatric familial mediterranean fever patients

Authors

  • Melek Tufek Sabuncuoglu Serafeddin Training and Research Hospital, Department of Ophthalmology, Amasya , Turkey
  • Nihat Aydin Sabuncuoglu Serafeddin Training and Research Hospital, Department of Ophthalmology, Amasya , Turkey
  • Mustafa Capraz Sabuncuoglu Serafeddin Training and Research Hospital, Department of Internal Medicine, Amasya, Turkey
  • Pinar Nalcacioglu Yıldırım Beyazıt University Medical School, Department of Ophthalmology, Ankara, Turkey
  • Irfan Akalin Trabzon Kanuni Training and Research Hospital, Department of Ophthalmology, Trabzon, Turkey

Keywords:

Choroid, familial mediterranean fever, optic nerve, optical coherence tomography

Abstract

Aim: We aimed to compare the ocular posterior segment parameters in pediatric patients with Familial Mediterranean Fever (FMF) with a healthy control group.

Materials and Method: We evaluated 40 pediatric FMF patients and 36 healthy children in this study. Choroidal thicknesses from the subfoveal, nasal and temporal 500 µm, 1000 µm, and 1500 µm points; the subfoveal macular thickness; macular volume; optic nerve head (ONH) parameters; and peripapillary retinal nerve fiber layer (RNFL) thickness were measured. An optical coherence tomography (OCT) device was used for measurements.

Results: The choroidal thickness in the temporal 1500 µm was significantly thinner, and average peripapillary RNFL thickness was significantly lower in the FMF group compared to the control group (p=0.015 and p=0.023, respectively). The groups were similar in terms of macular thickness and macular volume. Among the ONH parameters, the rim area thickness was also significantly higher in the FMF group (p= 0.013).

Conclusion: This study shows that the recurrent inflammation caused by FMF can affect choroidal thickness and peripapillary RNFL in children.

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Published

2022-04-29

Issue

Vol. 29 No. 4 (2022): April

Section

Original Articles

License

Copyright (c) 2022 The author(s)

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

CC Attribution-NonCommercial-NoDerivatives 4.0

How to Cite

1.
Evaluation of posterior segment ocular parameters in pediatric familial mediterranean fever patients. Ann Med Res [Internet]. 2022 Apr. 29 [cited 2025 May 13];29(4):310-4. Available from: http://www.annalsmedres.org/index.php/aomr/article/view/4158